Elderly Vulnerability to Infectious Diseases in Bangladesh: An Examination of Comorbidities, Hospital Stay, and Mortality

Main Article Content

Emtiaz Ahammed
Md Aminul Islam
Fahad Bin Akhter
Aliya Afsara Mim
Fahad Amin
Nahid Afrin Nisa

Abstract

Background: The elderly population in Bangladesh is growing at an unprecedented rate, with projections indicating that by 2050, 21.9% of the population will be aged 60 years and above. Objective: To describe the sociodemographic and clinical characteristics of elderly patients hospitalized due to infectious diseases in a tertiary care hospital in Bangladesh. Methods: This cross-sectional study was conducted at the Cumilla Medicare General Hospital, Cumilla, Bangladesh, from September 2023 to June 2024. 130 elderly patients (aged 60 years and above) hospitalized with infections were included. Data were collected on demographic variables, comorbidities, types of infections, length of hospital stay, and treatment outcomes. Statistical analysis was performed using descriptive statistics, with p-values calculated to assess the significance of associations. Results: Most patients were 60-69 years old (57.7%), with a higher proportion of males (57.7%). Urinary tract infections (UTIs) were the most common infection (34.6%), followed by pneumonia (23.1%) and respiratory tract infections (19.2%). Comorbidities, particularly hypertension and diabetes, were significantly associated with UTI (p=0.002 and p=0.015, respectively). The mean length of hospital stay was the longest for sepsis patients (10.5 days). Overall, 76.9% of patients recovered, while 15.4% were re-admitted, and 7.7% died during the hospital stay. Conclusion: This study highlights the significant burden of infectious diseases among elderly patients in Bangladesh. Urinary tract infections, pneumonia, and respiratory tract infections are the most prevalent, with comorbidities such as hypertension and diabetes contributing to increased vulnerability. These findings emphasize the need for targeted interventions to reduce the risk of infections and improve healthcare access for the elderly. 

Article Details

How to Cite
Ahammed, E. ., Islam, M. A. ., Akhter, F. B. ., Mim, A. A. ., Amin, F. ., & Nisa, N. A. . (2025). Elderly Vulnerability to Infectious Diseases in Bangladesh: An Examination of Comorbidities, Hospital Stay, and Mortality. Asia Pacific Journal of Surgical Advances, 2(1), 10-16. https://doi.org/10.70818/apjsa.2025.v02i01.014
Section
Original Research Articles

How to Cite

Ahammed, E. ., Islam, M. A. ., Akhter, F. B. ., Mim, A. A. ., Amin, F. ., & Nisa, N. A. . (2025). Elderly Vulnerability to Infectious Diseases in Bangladesh: An Examination of Comorbidities, Hospital Stay, and Mortality. Asia Pacific Journal of Surgical Advances, 2(1), 10-16. https://doi.org/10.70818/apjsa.2025.v02i01.014

References

1. HelpAge Asia. Aging Population In Bangladesh. 2020. [Online] [Accessed on 23 October 2020].

2. Atella V, Piano Mortari A, Kopinska J, Belotti F, Lapi F, et al. Trends in age-related disease burden and healthcare utilization. Aging cell. 2019;18(1):e12861.

3. Christensen KL, Holman RC, Steiner CA, Sejvar JJ, Stoll BJ, Schonberger LB. Infectious disease hospitalizations in the United States. Clinical infectious diseases. 2009;49(7):1025-1035.

4. Liang SY. Sepsis and other infectious disease emergencies in the elderly. Emergency Medicine Clinics. 2016;34(3):501-522.

5. Saliba W, Fediai A, Edelstein H, Markel A, Raz R. Trends in the burden of infectious disease hospitalizations among the elderly in the last decade. European Journal of Internal Medicine. 2013;24(6):536-540.

6. Quach C, McArthur M, McGeer A, Li L, Simor A, Dionne M, et al. Risk of infection following a visit to the emergency department: a cohort study. CMAJ. 2012;184(4):E232-239.

7. Nimri LF, Batchoun R. Community-acquired bacteremia in a rural area: predominant bacterial species and antibiotic resistance. Journal of medical microbiology. 2004;53(10):1045-1049.

8. Barikdar A, Ahmed T, Lasker SP. The situation of the elderly in Bangladesh. Bangladesh Journal of Bioethics. 2016;7(1):27-36

9. Ferdaus, F., Zahan, R., Rahman, M. A., & Chowdhury, S. (2020). A study on health-related risk factors and health-seeking behavior among elderly population in rural Bangladesh. Mediscope, 7(2), 75–81. https://doi.org/10.3329/mediscope.v7i2.49445

10. Rowe TA, Juthani-Mehta M. Urinary tract infection in older adults. Aging health. 2013 Oct;9(5):10.2217/ahe.13.38. doi: 10.2217/ahe.13.38. PMID: 24391677; PMCID: PMC3878051.

11. Petrie JR, Guzik TJ, Touyz RM. Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms. Can J Cardiol. 2018 May;34(5):575-584. doi: 10.1016/j.cjca.2017.12.005. Epub 2017 Dec 11. PMID: 29459239; PMCID: PMC5953551.

12. Charrada, I., Tahri, S., Boubaker, F., Arfa, S., Bougossa, R., Brahim, M. B., Zantour, B., Alaya, W., Berriche, O., & Sfar, M. H. (2019). Evolution of hypertension and diabetes in elderly subjects. Archives of Cardiovascular Diseases Supplements, 11(3), e334. https://doi.org/10.1016/j.acvdsp.2019.05.006

13. Westendorp WF, Nederkoorn PJ, Vermeij JD, Dijkgraaf MG, van de Beek D. Post-stroke infection: a systematic review and meta-analysis. BMC Neurol. 2011 Sep 20;11:110. doi: 10.1186/1471-2377-11-110. PMID: 21933425; PMCID: PMC3185266.

14. Kingren MS, Starr ME, Saito H. Divergent Sepsis Pathophysiology in Older Adults. Antioxid Redox Signal. 2021 Dec;35(16):1358-1375. doi: 10.1089/ars.2021.0056. Epub 2021 Oct 1. PMID: 34210173; PMCID: PMC8905233.

15. Liang SY. Sepsis and Other Infectious Disease Emergencies in the Elderly. Emerg Med Clin North Am. 2016 Aug;34(3):501-22. doi: 10.1016/j.emc.2016.04.005. PMID: 27475012; PMCID: PMC5022369.

16. Soraci L, Cherubini A, Paoletti L, Filippelli G, Luciani F, Laganà P, Gambuzza ME, Filicetti E, Corsonello A, Lattanzio F. Safety and Tolerability of Antimicrobial Agents in the Older Patient. Drugs Aging. 2023 Jun;40(6):499-526. doi: 10.1007/s40266-023-01019-3. Epub 2023 Mar 28. PMID: 36976501; PMCID: PMC10043546.

17. Matovelle P, Oliván-Blázquez B, Domínguez-García M, Casado-Vicente V, Pascual de la Pisa B, Magallón-Botaya R. Health Outcomes for Older Patients with Chronic Diseases During the First Pandemic Year. Clin Interv Aging. 2024 Mar 6;19:385-397. doi: 10.2147/CIA.S444716. PMID: 38464598; PMCID: PMC10924748.

18. Ferdaus, F., Zahan, R., Rahman, M. A., & Chowdhury, S. (2020a). A study on health related risk factors and health seeking behavior among elderly population in rural Bangladesh. Mediscope, 7(2), 75–81. https://doi.org/10.3329/mediscope.v7i2.49445

19. Hasan, H., Rahman, M. H. ., Haque, M. A., Rahman, M. S. ., Ali, M. S. ., & Sultana, S. . (2024). Nutritional Management in Patients with Chronic Kidney Disease: A Focus on Renal Diet. Asia Pacific Journal of Medical Innovations, 1(1), 34-40.

20. Chowdhury NR, Moname EJ, Al Azad G, Hani U, Nazmin F, Ferdaus F. Interplay Between Malnutrition and Infectious Diseases Insights from a Cross-Sectional Study in Bangladesh. Asia Pacific Journal of Medical Innovations. 2024;1(2):41-7.

21. Azad GA, Moname EJ, Chowdhury NR, Mondal S, Tisa AH, Ferdaus F. Co-Morbidity Landscape in Cancer Patients: Non-Communicable Disease Burden and Trends. Asia Pacific Journal of Medical Innovations. 2024;1(2):48-54.

22. Nazmin F, Roy A, Bushra T, Retina IJ, Arnab KH, Ferdaus F. Exploring the Prevalence and Social Determinants of ADHD and Comorbidities Among Urban School Aged Children in Bangladesh. Asia Pacific Journal of Medical Innovations. 2024;1(2):61-74.

23. Wohid F, Eme FW, Fahim IH, Mim M, Ferdaus F. Work Life Balance and Its Influence on Physical and Mental Health Among Female Teachers of Public University in Bangladesh. Asia Pacific Journal of Medical Innovations. 2024;1(2):68-75.

24. Mondal S, Arnab KH, Retina IJ, Bushra T, Roy A, Tisa AH, Ferdaus F. Mental Health Status and Stress Factors Among Junior Doctors in Public Hospitals in Bangladesh A Cross Sectional Analysis. Asia Pacific Journal of Surgical Advances. 2024;1(2):39-43.

25. Bushra T, Mondal S, Nazmin F, Arnab KH, Tisa AH, Roy A, Ferdaus F. Burden of Peptic Ulcer Disease Among Smoking and Non-Smoking Healthcare Providers A Comparative Cross-Sectional Study in Gazipur, Dhaka. Asia Pacific Journal of Surgical Advances. 2024;1(2):44-50.

26. Rima US, Islam J, Mim SI, Roy A, Dutta T, Dutta B, Ferdaus FF. Co-Infection of Tuberculosis and Diabetes: Implications for Treatment and Management. Asia Pacific Journal of Surgical Advances. 2024;1(2):51-8.

27. Arnab KH, Nazmin F, Mondal S, Tisa AH, Bushra T. Perceptions and Barriers to Breast Cancer Screening Among Women in Slum Areas: A Cross-Sectional Study. Asia Pacific Journal of Surgical Advances. 2024;1(2):59-65.

28. Karmakar S, Brinta MT. Assessing the Impact of Chronic Hypertension on Renal Function: A Cross-Sectional Study. Asia Pacific Journal of Surgical Advances. 2024;1(2):66-71.

29. Dutta B, Dutta T, Rima US, Islam J, Roy A, Mim SI, Ferdaus F. Burden of Antibiotic-Resistant Urinary Tract Infections in Rural Females: Insights from a Cross-Sectional Study in Bangladesh. Asia Pacific Journal of Surgical Advances. 2024;1(2):72-9.

30. Wohid F, Eme FW, Fahim IH, Mim M, Sultana T, Ferdaus F. Assessment of Nutrition Knowledge and Dietary Practices Among Non-Medical Students: A Cross-Sectional Study. Asia Pacific Journal of Surgical Advances. 2024;1(2):80-6.

31. Dias SP, Brouwer MC, van de Beek D. Sex and Gender Differences in Bacterial Infections. Infect Immun. 2022 Oct 20;90(10):e0028322. doi: 10.1128/iai.00283-22. Epub 2022 Sep 19. PMID: 36121220; PMCID: PMC9584217.

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